SupraHex: an R/Bioconductor package for tabular omics data analysis using a supra-hexagonal map.

ABSTRACT: Biologists are increasingly confronted with the challenge of quickly understanding genome-wide biological data, which usually involve a large number of genomic coordinates (e.g. genes) but a much smaller number of samples. To meet the need for data of this shape, we present an open-source package called 'supraHex' for training, analysing and visualising omics data. This package devises a supra-hexagonal map to self-organise the input data, offers scalable functionalities for post-analysing the map, and more importantly, allows for overlaying additional data for multilayer omics data comparisons. Via applying to DNA replication timing data of mouse embryogenesis, we demonstrate that supraHex is capable of simultaneously carrying out gene clustering and sample correlation, providing intuitiv

SUBMITTER: Fang H 

PROVIDER: S-EPMC3905187 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature