Lipoprotein lipase gene HindIII polymorphism and risk of myocardial infarction in South Indian population.

ABSTRACT:

Introduction

Studies have reported an association between lipoprotein lipase (LPL) gene and myocardial infarction in some populations. Therefore, the present study aimed to investigate the association of the HindIII polymorphism of the (LPL) gene with myocardial infarction and to explore its potential role in susceptibility in a South Indian population.

Subjects and methods

We included a total of 412 subjects (202 myocardial infarction patients and 210 age- and sex-matched controls). Demographic and clinical characteristics were collected. Lipid profiles were estimated. DNA was isolated and the LPL gene HindIII polymorphism was determined by polymerase chain reaction.

Results

Comparison of the lipid profiles between patients and controls showed that patients had stati

SUBMITTER: Tanguturi PR 

PROVIDER: S-EPMC3905261 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature