Association between CC10 +38A/G polymorphism and asthma risk: A meta-analysis.

ABSTRACT:

Objectives

A number of studies conducted to assess the association between Clara cell 10-kDa protein (CC10) +38A/G polymorphism and susceptibility to asthma have yielded inconsistent and inconclusive results. In the present study, the possible association was assessed by a meta-analysis.

Methods

Relevant articles were identified for the period ranging from Jan 1998 up to March 2013. Pooled odds ratios (OR) with 95% confidence intervals (CI) were appropriately derived from fixed effects or random-effects models.

Results

Ten case-control studies with a total of 1529 asthma cases and 2399 controls were included in this meta-analysis. The association between CC10 +38A/G polymorphism and asthma risk was determined in dominant model, recessive model, additive model, and cod

SUBMITTER: Zhao G 

PROVIDER: S-EPMC3905370 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature