Inhibitory activities of omega-3 Fatty acids and traditional african remedies on keloid fibroblasts.

ABSTRACT: Keloids develop when scar tissue responds to skin trauma with proliferative fibrous growths that extend beyond the boundaries of the original wound and progress for several months or years. Keloids most frequently occur in individuals of indigenous sub-Saharan African origin. The etiology for keloids is still unknown and treatment can be problematic as patients respond differently to various treatment modalities. Keloids have a high rate of recurrence following surgical excision. Some West African patients claim to have had successful outcomes with traditional African remedies-boa constrictor oil (BCO) and shea butter-leading the authors to investigate their effects on cultured fibroblasts. The effects of emulsions of BCO, fish oil, isolated omega-3 fatty acids, and shea butter were tested

SUBMITTER: Olaitan PB 

PROVIDER: S-EPMC3905615 | biostudies-literature | 2011 Apr

REPOSITORIES: biostudies-literature