Untreated sleep-disordered breathing: links to aging-related decline in sleep-dependent memory consolidation.

ABSTRACT:

Background

Increasing age is associated with a decline in cognition and motor skills, while at the same time exacerbating one's risk of developing obstructive sleep apnea (OSA). OSA-related cognitive deficits are highly prevalent and can affect various memory systems including overnight memory consolidation on a motor sequence task. Thus, the aim of our study was to examine the effect of aging on sleep-dependent motor memory consolidation in patients with and without OSA.

Methods

We studied 44 patients (19-68 years) who had been referred by a physician for a baseline polysomnography (PSG) evaluation. Based on their PSG, patients were assigned either to the OSA group (AHI>5/h), or control (Non-OSA) group (AHI<5/h). All subjects performed the Psychomotor Vigilance Task (PVT) a

SUBMITTER: Djonlagic I 

PROVIDER: S-EPMC3906012 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature