Current questions in HIV-associated lung cancer.

ABSTRACT:

Purpose of review

In this review, we explore current questions regarding risk factors contributing to frequent and early onset of lung cancer among populations with HIV infection, treatment, and outcomes of lung cancer in HIV-infected patients as well as challenges in a newly evolving era of lung cancer screening.

Recent findings

Lung cancer, seen in three-fold excess in HIV-infected populations, has become the most common non-AIDS defining malignancy in the highly active antiretroviral therapy era. HIV-associated lung cancer appears to be associated with young age at diagnosis, cigarette smoking, advanced stage at presentation, and a more aggressive clinical course. There is no unified explanation for these observations, and aside from traditional risk factors, HIV-related

SUBMITTER: Shcherba M 

PROVIDER: S-EPMC3906041 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature