A preliminary study of viral metagenomics of French bat species in contact with humans: identification of new mammalian viruses.

ABSTRACT: The prediction of viral zoonosis epidemics has become a major public health issue. A profound understanding of the viral population in key animal species acting as reservoirs represents an important step towards this goal. Bats harbor diverse viruses, some of which are of particular interest because they cause severe human diseases. However, little is known about the diversity of the global population of viruses found in bats (virome). We determined the viral diversity of five different French insectivorous bat species (nine specimens in total) in close contact with humans. Sequence-independent amplification, high-throughput sequencing with Illumina technology and a dedicated bioinformatics analysis pipeline were used on pooled tissues (brain, liver and lungs). Comparisons of the sequences

SUBMITTER: Dacheux L 

PROVIDER: S-EPMC3906132 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature