Ontology highlight
ABSTRACT:
SUBMITTER: Wong CC
PROVIDER: S-EPMC3906213 | biostudies-literature | 2014 Apr
REPOSITORIES: biostudies-literature
Wong C C Y CC Meaburn E L EL Ronald A A Price T S TS Jeffries A R AR Schalkwyk L C LC Plomin R R Mill J J
Molecular psychiatry 20130423 4
Autism spectrum disorder (ASD) defines a group of common, complex neurodevelopmental disorders. Although the aetiology of ASD has a strong genetic component, there is considerable monozygotic (MZ) twin discordance indicating a role for non-genetic factors. Because MZ twins share an identical DNA sequence, disease-discordant MZ twin pairs provide an ideal model for examining the contribution of environmentally driven epigenetic factors in disease. We performed a genome-wide analysis of DNA methyl ...[more]