Cognitive impairment and PD patients' capacity to consent to research.

ABSTRACT:

Objective

To examine how cognitive impairment affects Parkinson disease (PD) patients' research consent capacity.

Methods

A cross-sectional study of 90 patients with PD, divided using Mattis Dementia Rating Scale-2 scores into 3 groups of 30 (normal, borderline, and impaired), and 30 neurologically normal older adults completed 2 capacity interviews (an early-phase randomized and controlled drug trial and a sham-controlled surgical implantation of genetic tissue) using the MacArthur Competence Assessment Tool for Clinical Research. Expert clinicians used the interviews to classify the patients as either capable or not capable of providing their own informed consent. These judgments were compared with performance on the Montreal Cognitive Assessment (MoCA) and the Mini-Mental

SUBMITTER: Karlawish J 

PROVIDER: S-EPMC3908465 | biostudies-literature | 2013 Aug

REPOSITORIES: biostudies-literature