Do mismatches between pre- and post-natal environments influence adult physiological functioning?

ABSTRACT:

Purpose

Mismatches between pre- and post-natal environments have implications for disease in adulthood. However, less is known about how this mismatch can affect physiological systems more generally, especially at younger ages. We hypothesised that mismatches between pre- and post-natal environments, as measured by the measures of birthweight and adult leg length, would be associated with poorer biomarker levels across five key physiological systems in young adults.

Methods

Data were collected from 923, 36 year-old respondents from the West of Scotland Twenty-07 Study. The biomarkers were: systolic blood pressure (sBP); forced expiratory volume (FEV1); glycated haemoglobin (HbA1c); glomerular filtration rate (eGFR); and gamma-glutamyltransferase (GGT). These biomarkers were

SUBMITTER: Robertson T 

PROVIDER: S-EPMC3908925 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature