Reduced error-related activation of dorsolateral prefrontal cortex across pediatric anxiety disorders.

ABSTRACT:

Objective

Abnormalities of cognitive control functions, such as conflict and error monitoring, have been theorized to underlie obsessive-compulsive symptoms but only recently have been considered a potentially relevant psychological construct for understanding other forms of anxiety. The authors sought to determine whether these cognitive control processes elicit the same abnormalities of brain function in patients with pediatric obsessive-compulsive disorder (OCD) as in those with non-OCD anxiety disorders.

Method

Functional magnetic resonance imaging of the Multisource Interference Task was used to measure conflict- and error-related activations in youth (8-18 years) with OCD (n = 21) and non-OCD anxiety disorders (generalized anxiety disorder, social phobia, separation an

SUBMITTER: Fitzgerald KD 

PROVIDER: S-EPMC3910489 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature