Obstructive sleep apnea and risk of cardiovascular events and all-cause mortality: a decade-long historical cohort study.

ABSTRACT:

Background

Obstructive sleep apnea (OSA) has been reported to be a risk factor for cardiovascular (CV) disease. Although the apnea-hypopnea index (AHI) is the most commonly used measure of OSA, other less well studied OSA-related variables may be more pathophysiologically relevant and offer better prediction. The objective of this study was to evaluate the relationship between OSA-related variables and risk of CV events.

Methods and findings

A historical cohort study was conducted using clinical database and health administrative data. Adults referred for suspected OSA who underwent diagnostic polysomnography at the sleep laboratory at St Michael's Hospital (Toronto, Canada) between 1994 and 2010 were followed through provincial health administrative data (Ontario, Canada) u

SUBMITTER: Kendzerska T 

PROVIDER: S-EPMC3913558 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature