The relationship of initial transferrin saturation to cardiovascular parameters and outcomes in patients initiating dialysis.

ABSTRACT:

Background

The prognostic importance of anemia for cardiovascular (CV) events and mortality has been extensively investigated. However, little is known about the impact of transferrin saturation (TSAT), a marker reflecting the availability of iron for erythropoiesis, on clinical outcome in dialysis patients.

Methods

A total of 879 anemic incident dialysis patients were recruited from the Clinical Research Center for End-Stage Renal Disease in Korea and were divided into 3 groups according to baseline TSAT of ≤20%, 20-40%, and >40%.

Results

There were no differences in hemoglobin levels and the proportion of patients on erythropoiesis-stimulating agents or iron supplements among the 3 groups. During a mean follow-up duration of 19.3 months, 51 (5.8%) patients died. CV

SUBMITTER: Koo HM 

PROVIDER: S-EPMC3914817 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature