Relationship between humoral response against hepatitis C virus and disease overcome.

ABSTRACT:

Abstract

Hepatitis C virus infection leads to liver disease whose severity can range from mild to serious lifelong illness. However the parameters involved in the evolution of the disease are still unknown. Among other factors, the virus-elicited antibody profile is suspected to play a role in the outcome of the disease. Analysis of the relationship between anti-virus antibodies and disease state requires the analysis of a large number of serums from patients (hepatitis C virus+) and of epitopes from the viral proteins. Such a study would benefit from microarray-based screening systems that are appropriate for high-throughput assays. We used a method combining peptide chips and surface plasmon resonance imaging previously shown to be suitable for analyzing complex mediums and detec

SUBMITTER: Brakha C 

PROVIDER: S-EPMC3915053 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature