Evaluating the effectiveness of fish consumption advisories: modeling prenatal, postnatal, and childhood exposures to persistent organic pollutants.

ABSTRACT:

Background

Because human exposure to persistent organic pollutants (POPs) occurs mainly through ingestion of contaminated food, regulatory bodies issue dietary consumption advisories to describe safe intake levels for food items of concern, particularly fish.

Objectives

Our study goal was to estimate the effectiveness of fish consumption advisories in reducing exposure of infants and children to POPs.

Methods

We used the time-variant mechanistic model CoZMoMAN to estimate and compare prenatal, postnatal, and childhood exposure to polychlorinated biphenyl congener PCB-153 under different scenarios of maternal guideline adherence for both hypothetical constant and realistic time-variant chemical emissions. The scenarios differed in terms of length of compliance (1 vs. 5

SUBMITTER: Binnington MJ 

PROVIDER: S-EPMC3915257 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature