Minimum-norm cortical source estimation in layered head models is robust against skull conductivity error.

ABSTRACT: The conductivity profile of the head has a major effect on EEG signals, but unfortunately the conductivity for the most important compartment, skull, is only poorly known. In dipole modeling studies, errors in modeled skull conductivity have been considered to have a detrimental effect on EEG source estimation. However, as dipole models are very restrictive, those results cannot be generalized to other source estimation methods. In this work, we studied the sensitivity of EEG and combined MEG+EEG source estimation to errors in skull conductivity using a distributed source model and minimum-norm (MN) estimation. We used a MEG/EEG modeling set-up that reflected state-of-the-art practices of experimental research. Cortical surfaces were segmented and realistically-shaped three-layer anatomica

SUBMITTER: Stenroos M 

PROVIDER: S-EPMC3915841 | biostudies-literature | 2013 Nov

REPOSITORIES: biostudies-literature