Oxylipin diversity in the diatom family Leptocylindraceae reveals DHA derivatives in marine diatoms.

ABSTRACT: Marine planktonic organisms, such as diatoms, are prospective sources of novel bioactive metabolites. Oxygenated derivatives of fatty acids, generally referred to as oxylipins, in diatoms comprise a highly diverse and complex family of secondary metabolites. These molecules have recently been implicated in several biological processes including intra- and inter-cellular signaling as well as in defense against biotic stressors and grazers. Here, we analyze the production and diversity of C20 and C22 non-volatile oxylipins in five species of the family Leptocylindraceae, which constitute a basal clade in the diatom phylogeny. We report the presence of species-specific lipoxygenase activity and oxylipin patterns, providing the first demonstration of enzymatic production of docosahexaenoic aci

SUBMITTER: Nanjappa D 

PROVIDER: S-EPMC3917278 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature