Clinical and laboratory factors that predict death in very low birth weight infants presenting with late-onset sepsis.

ABSTRACT:

Background

Late-onset sepsis (LOS) in very low birth weight (VLBW) infants is associated with significant morbidity and mortality. The ability to predict mortality in infants with LOS based on clinical and laboratory factors at presentation of illness remains limited.

Objectives

To identify predictors of sepsis-associated mortality from a composite risk profile that includes demographic data, category of infecting organism, clinical and laboratory data at onset of illness.

Study design

Data were collected from VLBW infants with at least 1 episode of LOS admitted to Yale Neonatal Intensive Care Unit from 1989 through 2007. Episodes were categorized as Gram-positive, Gram-negative or fungal. Multivariate logistic regression analysis was used to compare and contrast diff

SUBMITTER: Levit O 

PROVIDER: S-EPMC3917323 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature