Modeling seroadaptation and sexual behavior among HIV+ study participants with a simultaneously multilevel and multivariate longitudinal count model.

ABSTRACT: Longitudinal behavioral intervention trials to reduce HIV transmission risk collect complex multilevel and multivariate data longitudinally for each subject with important correlation structures across time, level, and variables. Accurately assessing the effects of these trials are critical for determining which interventions are effective. Both numbers of partners and numbers of sex acts with each partner are reported at each time point. Sex acts with each partner are further differentiated into protected and unprotected acts with correspondingly differing risks of HIV/STD transmission. These trials generally also have eligibility criteria limiting enrollment to participants with some minimal level of risky sexual behavior tied directly to the outcome of interest. The combination of these

SUBMITTER: Zhu Y 

PROVIDER: S-EPMC3917561 | biostudies-literature | 2013 Mar

REPOSITORIES: biostudies-literature