Initial effects of the National PCV7 Childhood Immunization Program on adult invasive pneumococcal disease in Israel.

ABSTRACT:

Background

PCV7 was introduced as universal childhood vaccination in Israel in July 2009 and PCV13 in November 2010. Here we report data on adult invasive pneumococcal disease (IPD), two years post PCV7 implementation and before an expected effect of PCV13.

Methods

An ongoing nationwide active-surveillance (all 27 laboratories performing blood cultures in Israel), providing all blood & CSF S. pneumoniae isolates from persons >18 y was initiated in July 2009. Capture-recapture method assured reporting of >95% cases. All isolates were serotyped in one central laboratory. IPD outcome and medical history were recorded in 90%. Second year post PCV implementation is compared to the first year.

Results

During July 2009 to June 2011, 970 IPD cases were reported (annual incide

SUBMITTER: Regev-Yochay G 

PROVIDER: S-EPMC3917916 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature