Identifying which septic patients have increased mortality risk using severity scores: a cohort study.

ABSTRACT:

Background

Early aggressive therapy can reduce the mortality associated with severe sepsis but this relies on prompt recognition, which is hindered by variation among published severity criteria. Our aim was to test the performance of different severity scores in predicting mortality among a cohort of hospital inpatients with sepsis.

Methods

We anonymously linked routine outcome data to a cohort of prospectively identified adult hospital inpatients with sepsis, and used logistic regression to identify associations between mortality and demographic variables, clinical factors including blood culture results, and six sets of severity criteria. We calculated performance characteristics, including area under receiver operating characteristic curves (AUROC), of each set of severi

SUBMITTER: Marwick CA 

PROVIDER: S-EPMC3918178 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature