Magnetic and optical properties of multifunctional core-shell radioluminescence nanoparticles.

ABSTRACT: When X-rays irradiate radioluminescence nanoparticles, they generate visible and near infrared light that can penetrate through centimeters of tissue. X-ray luminescence tomography (XLT) maps the location of these radioluminescent contrast agents at high resolution by scanning a narrow X-ray beam through the tissue sample and collecting the luminescence at every position. Adding magnetic functionality to these radioluminescent particles would enable them to be guided, oriented, and heated using external magnetic fields, while their location and spectrum could be imaged with XLT and complementary magnetic resonance imaging. In this work, multifunctional monodispersed magnetic radioluminescent nanoparticles were developed as potential drug delivery carriers and radioluminescence imaging agen

SUBMITTER: Chen H 

PROVIDER: S-EPMC3918467 | biostudies-literature | 2012 Jul

REPOSITORIES: biostudies-literature