Plasmid-templated shape control of condensed DNA-block copolymer nanoparticles.

ABSTRACT: DNA-containing micellar nanoparticles with distinctly different and highly uniform morphologies are prepared via condensation of plasmid DNA with a block copolymer of polyethylene glycol and a polycation in solvents of different polarity. Molecular dynamics simulations explain the underlying mechanism.

SUBMITTER: Jiang X 

PROVIDER: S-EPMC3918481 | biostudies-literature | 2013 Jan

REPOSITORIES: biostudies-literature