Resting state functional connectivity of the ventral attention network in children with a history of depression or anxiety.

ABSTRACT:

Objective

We examined whether depression and anxiety disorders in early childhood were associated with changes in resting state functional connectivity (RSFC) of the ventral attention network (VAN), and whether RSFC in the VAN was associated with alterations in attention specific to these disorders. Important clinical features of these illnesses, including changes in attention toward novel stimuli and changes in attention to stimuli of negative valence (threat/sad bias), indirectly implicate the VAN.

Method

We collected resting state functional magnetic resonance imaging data in children aged 8 to 12 years. Data were volume censored to reduce artifact from submillimeter movement, resulting in analyzable data from 30 children with a history of depression and/or anxiety and 42

SUBMITTER: Sylvester CM 

PROVIDER: S-EPMC3918493 | biostudies-literature | 2013 Dec

REPOSITORIES: biostudies-literature