Characteristics associated with informed consent for genetic studies in the ACCORD trial.

ABSTRACT:

Background

Prior studies found that some groups have lower genetic consent rates than others. Participant consent for genetic studies enables randomized trials to examine effects of interventions compared to control in participants with different genotypes.

Methods

Unadjusted and multivariate associations between genetic consent rates and participant, study, and consent characteristics in 9573 participants approached for genetics consent in the multicenter Action to Control Cardiovascular Risk in Diabetes (ACCORD) trial, which used a layered genetics consent.

Results

Eighty-nine percent of eligible participants consented to genetic studies ("Any Consent") and 64.7% consented to studies of any genes by any investigator ("Full Consent"), with similar rates in randomized

SUBMITTER: Simons-Morton DG 

PROVIDER: S-EPMC3918951 | biostudies-literature | 2014 Jan

REPOSITORIES: biostudies-literature