Effects of statins on incident dementia in patients with type 2 DM: a population-based retrospective cohort study in Taiwan.

ABSTRACT:

Background

Patients with Type 2 diabetes (T2DM) are prone to develop dementia. Results from a recent study indicated that statin users had lower chance of developing incident dementia. However there is little information on the potential benefits of statin use on dementia in patients with T2DM cohort.

Method

A population-based retrospective study using a nationwide cohort of National Health Insurance Research Database in Taiwan was performed. T2DM cohort with regular use of statins was followed up to 8 years. Multivariate cox-proportional hazards regression model was used to estimate the association between statin use and incidence of dementia including Alzheimer's disease and non-Alzheimer dementia after adjusting for several potential confounders.

Results

Among 28,3

SUBMITTER: Chen JM 

PROVIDER: S-EPMC3919769 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature