Screening of differentially expressed genes associated with non-union skeletal fractures and analysis with a DNA microarray.

ABSTRACT: The purpose of this study was to identify the feature genes that are associated with non-union skeletal fractures using samples of normal union and non-union skeletal fracture microarray data. The gene expression profile GSE494 was downloaded from the Gene Expression Omnibus database and included 12 samples based on three different platforms (GPL92, GPL93 and GPL8300). Each of the platforms had four sets of expression data, two from normal union skeletal fracture samples and two from non-union skeletal fracture samples. The differentially expressed genes within the three platforms of expression data were identified using packages in R language and the differentially expressed genes common to the three platforms were selected. The selected common differentially expressed genes were further

SUBMITTER: Xu J 

PROVIDER: S-EPMC3919922 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature