Findings from the Quebec Family Study on the Etiology of Obesity: Genetics and Environmental Highlights.

ABSTRACT: The Quebec Family Study (QFS) was an observational study with three cycles of data collection between 1979 and 2002 in Quebec City, Canada. The cohort is a mixture of random sampling and ascertainment through obese individuals. The study has significantly contributed to our understanding of the determinants of obesity and associated disease risk over the past 35 years. In particular, the QFS cohort was used to investigate the contribution of familial resemblance and genetic effects on body fatness and behaviors related to energy balance. Significant familial aggregation and genetic heritability were reported for total adiposity, fat-free mass, subcutaneous fat distribution, abdominal and visceral fat, resting metabolic rate, physical activity level and other behavioral traits. The resource

SUBMITTER: Chaput JP 

PROVIDER: S-EPMC3920031 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature