Cytokine polymorphisms are associated with poor sleep maintenance in adults living with human immunodeficiency virus/acquired immunodeficiency syndrome.

ABSTRACT:

Study objectives

Cytokine activity and polymorphisms have been associated with sleep outcomes in prior animal and human research. The purpose of this study was to determine whether circulating plasma cytokines and cytokine polymorphisms are associated with the poor sleep maintenance commonly experienced by adults living with human immunodeficiency virus/acquired immunodeficiency syndrome (HIV/AIDS).

Design

Cross-sectional descriptive study.

Setting

HIV clinics and community sites in the San Francisco Bay area.

Participants

A convenience sample of 289 adults (193 men, 73 women, and 23 transgender) living with HIV/AIDS.

Interventions

None.

Measurements and results

A wrist actigraph was worn for 72 h to estimate the percentage of wake after sleep ons

SUBMITTER: Lee KA 

PROVIDER: S-EPMC3920310 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature