Preliminary functional MRI neural correlates of executive functioning and empathy in children with obstructive sleep apnea.

ABSTRACT:

Background

Pediatric obstructive sleep apnea (OSA) is associated with neurocognitive deficits. However, the neural substrates underlying such deficits remain unknown.

Methods

To examine executive control and emotional processing in OSA, 10 children age 7 to 11 y with polysomnographically diagnosed OSA and 7 age- and sex-matched controls underwent a color-word Stroop task and an empathy task consisting of dynamic visual scenarios depicting interpersonal harm or neutral actions in a magnetic resonance imaging (MRI) scanner. Functional MRI data were processed using MATLAB 7.12 with SPM8 for region of interest (ROI) analyses, and a general linear model was used with regressors for each trial type in each task.

Results

For the Stroop task, accuracy was similar in the two g

SUBMITTER: Kheirandish-Gozal L 

PROVIDER: S-EPMC3920325 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature