Long-term survival and dialysis dependency following acute kidney injury in intensive care: extended follow-up of a randomized controlled trial.

ABSTRACT:

Background

The incidence of acute kidney injury (AKI) is increasing globally and it is much more common than end-stage kidney disease. AKI is associated with high mortality and cost of hospitalisation. Studies of treatments to reduce this high mortality have used differing renal replacement therapy (RRT) modalities and have not shown improvement in the short term. The reported long-term outcomes of AKI are variable and the effect of differing RRT modalities upon them is not clear. We used the prolonged follow-up of a large clinical trial to prospectively examine the long-term outcomes and effect of RRT dosing in patients with AKI.

Methods and findings

We extended the follow-up of participants in the Randomised Evaluation of Normal vs. Augmented Levels of RRT (RENAL) study fr

SUBMITTER: Gallagher M 

PROVIDER: S-EPMC3921111 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature