Association between IL-10 gene polymorphisms and susceptibility of tuberculosis: evidence based on a meta-analysis.

ABSTRACT:

Background

A number of observational studies have been conducted to investigate the association of IL-10 gene polymorphisms with tuberculosis (TB) susceptibility. However, the results of different studies were inconsistent. The aim of this study was to investigate the relationship between IL-10 -1082G/A, -819T/C, and -592A/C polymorphisms and TB risk by meta-analysis.

Methods

A literature search was conducted among six English databases (PubMed, Embase, Web of Science, Science Direct, SpringerLink and EBSCO) and two Chinese databases (Wanfang and Chinese National Knowledge Infrastructure databases) to identify studies involving association between IL-10 -1082G/A, -819T/C, and -592A/C polymorphisms and TB susceptibility before May. 2013. Statistical analysis was performed usi

SUBMITTER: Liang B 

PROVIDER: S-EPMC3921162 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature