Anti-VEGF agents with or without antimetabolites in trabeculectomy for glaucoma: a meta-analysis.

ABSTRACT:

Purpose

We aimed to evaluate the intraoperative application of antimetabolites compared with anti-vascular endothelial growth factor (VEGF) agents with or without antimetabolites in trabeculectomy (Trab) for glaucoma.

Methods

Relevant studies were selected through extensive search using PubMed, EMBASE, the Cochrane Library, and Web of Science databases in August 2013. The primary efficacy estimate was measured using weighted mean difference of the percentage of intraocular pressure reduction (IOPR%) from baseline to end-point, and the secondary efficacy estimates were odds ratio (OR) and 95% confidence interval (CI) for complete success rate and qualified success rate. ORs were also used to measure the tolerability estimate for adverse events. Meta-analyses of fixed or rando

SUBMITTER: Xiong Q 

PROVIDER: S-EPMC3921170 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature