Novel hepatocellular carcinoma molecules with prognostic and therapeutic potentials.

ABSTRACT: Hepatocellular carcinoma (HCC), the predominant form of primary liver cancer, is the sixth most common cancer worldwide and the third leading cause of cancer-related death. The difficulty to diagnose early cancer stages, the aggressive behaviors of HCC, and the poor effectiveness of therapeutic treatments, represent the reasons for the quite similar deaths per year and incidence number. Considering the fact that the diagnosis of HCC typically occurs in the advanced stages of the disease when the therapeutic options have only modest efficacy, the possibility to identify early diagnostic markers could be of significant benefit. So far, a large number of biomarkers have been associated to HCC progression and aggressiveness, but many of them turned out not to be of practical utility. This is t

SUBMITTER: Scaggiante B 

PROVIDER: S-EPMC3921509 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature