Characterizing HIV manifestations and treatment outcomes of perinatally infected adolescents in Asia.

ABSTRACT:

Background

More perinatally HIV-infected children in Asia are reaching adolescence.

Methods

We analyzed data from July 1991 to March 2011 reported by 18 clinics in 6 countries of children age >12 years.

Results

Of 1254 adolescents, 33 (2.6%) died, and 52 (4.1%) were lost to follow-up within 2.4-year (3566 person-years) median follow-up period. Of 1061 adolescents under active follow-up, 485 (46%) were male, median (interquartile range) age was 14.7 (13.3-16.4) years, 73% had lost a parent(s), 93% attended school and 62% were aware of their HIV status. At the most recent evaluation, 93% were receiving highly active antiretroviral therapy, 71% (N = 737/1035) had CD4 ≥ 500 cells/mm(3) and 87% (N = 718/830) had viral load (VL) <400 copies/mL. Current CD4 ≥ 200 cells/mm(3)

SUBMITTER: Chokephaibulkit K 

PROVIDER: S-EPMC3922889 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature