Lack of association of P2RX7 gene rs2230912 polymorphism with mood disorders: a meta-analysis.

ABSTRACT:

Background

To assess the association of P2RX7 gene rs2230912 polymorphism with mood disorders using a meta-analysis.

Methods

Data were collected from the following electronic databases: PubMed, Excerpta Medica Database, Elsevier Science Direct, Cochrane Library, and Chinese Biomedical Literature Database, with the last report up to April 1, 2013. Odds ratio (OR) with 95% confidence interval (CI) was used to assess the strength of the association. Dependent on the results of heterogeneity test among individual studies, the fixed effect model (Mantel-Haenszel) or random effect model (DerSimonian-Laird) was selected to summarize the pooled OR.

Results

We identified 13 separate studies using search (6,962 cases and 9,262 controls). We detected significant between-study he

SUBMITTER: Feng WP 

PROVIDER: S-EPMC3922924 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature