Oxytocin receptor gene variation predicts empathic concern and autonomic arousal while perceiving harm to others.

ABSTRACT: Recent research indicates that the neuropeptide oxytocin and the gene for the oxytocin receptor (OXTR) have been implicated in the modulation of various social behaviors, including those related to empathy and sensitivity to others. In this study, we examine the hypothesis that genetic variation in OXTR is associated with autonomic reactions when perceiving others in distress. We also explore the possibility that individual disposition in empathic concern would differ by OXTR genotype. To address these questions, 51 male participants (18-35 years of age), genotyped for OXTR rs53576, viewed a social interaction containing high levels of individual distress and apparent physical pain. Electrodermal activity, a measure of sympathetic nervous system activity, was collected during the presentat

SUBMITTER: Smith KE 

PROVIDER: S-EPMC3923324 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature