Kassiopeia: a database and web application for the analysis of mutually exclusive exomes of eukaryotes.

ABSTRACT:

Background

Alternative splicing is an important process in higher eukaryotes that allows obtaining several transcripts from one gene. A specific case of alternative splicing is mutually exclusive splicing, in which exactly one exon out of a cluster of neighbouring exons is spliced into the mature transcript. Recently, a new algorithm for the prediction of these exons has been developed based on the preconditions that the exons of the cluster have similar lengths, sequence homology, and conserved splice sites, and that they are translated in the same reading frame.

Description

In this contribution we introduce Kassiopeia, a database and web application for the generation, storage, and presentation of genome-wide analyses of mutually exclusive exomes. Currently, Kassiopeia pro

SUBMITTER: Hatje K 

PROVIDER: S-EPMC3923563 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature