P300 development across the lifespan: a systematic review and meta-analysis.

ABSTRACT:

Background

The P300 component of the event-related potential is a large positive waveform that can be extracted from the ongoing electroencephalogram using a two-stimuli oddball paradigm, and has been associated with cognitive information processing (e.g. memory, attention, executive function). This paper reviews the development of the auditory P300 across the lifespan.

Methodology/principal findings

A systematic review and meta-analysis on the P300 was performed including 75 studies (n = 2,811). Scopus was searched for studies using healthy subjects and that reported means of P300 latency and amplitude measured at Pz and mean age. These findings were validated in an independent, existing cross-sectional dataset including 1,572 participants from ages 6-87. Curve-fitting proc

SUBMITTER: van Dinteren R 

PROVIDER: S-EPMC3923761 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature