Efficacy and safety of therapies for acute ischemic stroke in China: a network meta-analysis of 13289 patients from 145 randomized controlled trials.

ABSTRACT:

Background

Many of these therapies have been compared against placebos, but have not been directly compared against each other. To evaluate the efficacy and safety of several commonly used drugs for AIS directly or indirectly.

Methods

A systematic literature review was performed to identify randomized controlled trials (RCTs) published prior to April 2013 for AIS therapies. The primary outcome measures were the National Institutes of Health Stroke Scale (NIHSS) scores and the clinical effective rate. A fixed-effects meta-analysis and meta-regression are performed; lastly, performed a mixed treatment comparison was performed through the Bayesian methods.

Results

Outcome of efficacy of therapies for acute ischemic stroke are as followed: All of the therapies mentioned a

SUBMITTER: Yang B 

PROVIDER: S-EPMC3923787 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature