Untangling therapeutic ingredients of a personalized intervention for patients with depression and severe COPD.

ABSTRACT:

Objective

We developed a personalized intervention for depressed patients with COPD (PID-C) aimed to mobilize patients to participate in the care of both conditions. We showed that PID-C reduced depressive symptoms and dyspnea-related disability more than usual care over 28 weeks. This study focused on untangling key therapeutic ingredients of PID-C.

Design

Randomized controlled trial.

Setting

Community.

Participants

138 patients who received the diagnoses of COPD and major depression after screening 898 consecutive admissions for acute inpatient pulmonary rehabilitation.

Intervention

Nine sessions of PID-C compared with usual care over 28 weeks.

Measurements

Primary outcome measures were the 17-item Hamilton Depression Rating Scale and the Pulmon

SUBMITTER: Alexopoulos GS 

PROVIDER: S-EPMC3923856 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature