Genomic changes under rapid evolution: selection for parasitoid resistance.

ABSTRACT: In this study, we characterize changes in the genome during a swift evolutionary adaptation, by combining experimental selection with high-throughput sequencing. We imposed strong experimental selection on an ecologically relevant trait, parasitoid resistance in Drosophila melanogaster against Asobara tabida. Replicated selection lines rapidly evolved towards enhanced immunity. Larval survival after parasitization increased twofold after just five generations of selection. Whole-genome sequencing revealed that the fast and strong selection response in innate immunity produced multiple, highly localized genomic changes. We identified narrow genomic regions carrying a significant signature of selection, which were present across all chromosomes and covered in total less than 5% of the whole

SUBMITTER: Jalvingh KM 

PROVIDER: S-EPMC3924063 | biostudies-literature | 2014 Mar

REPOSITORIES: biostudies-literature