The association between malaria and iron status or supplementation in pregnancy: a systematic review and meta-analysis.

ABSTRACT:

Introduction

Malaria prevention and iron supplementation are associated with improved maternal and infant outcomes. However, evidence from studies in children suggests iron may adversely modify the risk of malaria. We reviewed the evidence in pregnancy of the association between malaria and markers of iron status, iron supplementation or parenteral treatment.

Methods and findings

We searched MEDLINE, EMBASE, the Cochrane Central Register of Controlled Trials, the Global Health Library, and the Malaria in Pregnancy library to identify studies that investigated the association between iron status, iron treatment or supplementation during pregnancy and malaria. Thirty one studies contributed to the analysis; 3 experimental and 28 observational studies. Iron supplementation was

SUBMITTER: Sangare L 

PROVIDER: S-EPMC3925104 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature