Migration-selection balance at multiple Loci and selection on dominance and recombination.

ABSTRACT: A steady influx of a single deleterious multilocus genotype will impose genetic load on the resident population and leave multiple descendants carrying various numbers of the foreign alleles. Provided that the foreign types are rare at equilibrium, and all immigrant genes are eventually eliminated by selection, the population structure can be inferred explicitly from the branching process taking place within a single immigrant lineage. Unless the migration and recombination rates were high, this novel method gives a close approximation to the simulation with all possible multilocus genotypes considered. Once the load and the foreign genotypes frequencies are known, it becomes possible to estimate selection acting on the invading modifiers of (i) dominance and (ii) recombination rate on the

SUBMITTER: Yanchukov A 

PROVIDER: S-EPMC3925130 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature