Simultaneous EEG-fMRI reveals a temporal cascade of task-related and default-mode activations during a simple target detection task.

ABSTRACT: Focused attention continuously and inevitably fluctuates, and to completely understand the mechanisms responsible for these modulations it is necessary to localize the brain regions involved. During a simple visual oddball task, neural responses measured by electroencephalography (EEG) modulate primarily with attention, but source localization of the correlates is a challenge. In this study we use single-trial analysis of simultaneously-acquired scalp EEG and functional magnetic resonance image (fMRI) data to investigate the blood oxygen level dependent (BOLD) correlates of modulations in task-related attention, and we unravel the temporal cascade of these transient activations. We hypothesize that activity in brain regions associated with various task-related cognitive processes modulates

SUBMITTER: Walz JM 

PROVIDER: S-EPMC3926909 | biostudies-literature | 2014 Nov

REPOSITORIES: biostudies-literature