Oral antimycobacterial therapy in chronic cutaneous sarcoidosis: a randomized, single-masked, placebo-controlled study.

ABSTRACT:

Importance

Sarcoidosis is a chronic granulomatous disease for which there are limited therapeutic options. This is the first randomized, placebo-controlled study to demonstrate that antimycobacterial therapy reduces lesion diameter and disease severity among patients with chronic cutaneous sarcoidosis.

Objective

To evaluate the safety and efficacy of once-daily antimycobacterial therapy on the resolution of chronic cutaneous sarcoidosis lesions.

Design and participants

A randomized, placebo-controlled, single-masked trial on 30 patients with symptomatic chronic cutaneous sarcoidosis lesions deemed to require therapeutic intervention.

Setting

A tertiary referral dermatology center in Nashville, Tennessee.

Interventions

Participants were randomized to rece

SUBMITTER: Drake WP 

PROVIDER: S-EPMC3927541 | biostudies-literature | 2013 Sep

REPOSITORIES: biostudies-literature