Treatments for macular oedema following central retinal vein occlusion: systematic review.

ABSTRACT:

Objectives

To review systematically the randomised controlled trial (RCT) evidence for treatment of macular oedema due to central retinal vein occlusion (CRVO).

Data sources

MEDLINE, EMBASE, CDSR, DARE, HTA, NHSEED, CENTRAL and meeting abstracts (January 2005 to March 2013).

Study eligibility criteria, participants and interventions

RCTs with at least 12 months of follow-up assessing pharmacological treatments for CRVO were included with no language restrictions.

Study appraisal and synthesis methods

2 authors screened titles and abstracts and conducted data extracted and Cochrane risk of bias assessment. Meta-analysis was not possible due to lack of comparable studies.

Results

8 studies (35 articles, 1714 eyes) were included, assessing aflibercept (n=2)

SUBMITTER: Ford JA 

PROVIDER: S-EPMC3927713 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature