Noninvasive ventilation as a weaning strategy for mechanical ventilation in adults with respiratory failure: a Cochrane systematic review.

ABSTRACT:

Background

Noninvasive ventilation has been studied as a means of reducing complications among patients being weaned from invasive mechanical ventilation. We sought to summarize evidence comparing noninvasive and invasive weaning and their effects on mortality.

Methods

We identified relevant randomized and quasirandomized trials through searches of databases, conference proceedings and grey literature. We included trials comparing extubation and immediate application of noninvasive ventilation with continued invasive weaning in adults on mechanical ventilation. Two reviewers each independently screened citations, assessed trial quality and abstracted data. Our primary outcome was mortality.

Results

We identified 16 trials involving 994 participants, most of whom had c

SUBMITTER: Burns KE 

PROVIDER: S-EPMC3928231 | biostudies-literature | 2014 Feb

REPOSITORIES: biostudies-literature