The burden of nephrotoxic drug prescriptions in patients with chronic kidney disease: a retrospective population-based study in Southern Italy.

ABSTRACT:

Background

The use of nephrotoxic drugs can further worsening renal function in chronic kidney disease (CKD) patients. It is therefore imperative to explore prescribing practices that can negatively affect CKD patients.

Aim

To analyze the use of nephrotoxic drugs in CKD patients in a general population of Southern Italy during the years 2006-2011.

Methods

The general practice "Arianna" database contains data from 158,510 persons, registered with 123 general practitioners (GPs) of Caserta. CKD patients were identified searching: CKD-related ICD-9 CM codes among causes of hospitalization; CKD-relevant procedures undergone in hospital (e.g. dialysis); drug prescriptions issued for a CKD-related indication. A list of nephrotoxic drugs was compiled and validated by pharmac

SUBMITTER: Ingrasciotta Y 

PROVIDER: S-EPMC3928406 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature