Association of vitamin D and incident statin induced myalgia--a retrospective cohort study.

ABSTRACT:

Background and objectives

Evidence is conflicting with regards to the role of vitamin D in statin induced myalgia (SIM). Studies so far have assessed cross-sectional association and were limited by study sample selected predominantly from cardiology clinics. In this retrospective cohort study we assessed the association between vitamin D and SIM and attempted to establish a serum vitamin D cutoff to identify patients at risk for developing SIM.

Methods

Medical charts of 5526 consecutive patients from a primary care practice in Scranton, Pennsylvania from 2005-2012 were reviewed. Vitamin D level (25-hydroxy cholecalciferol) at statin initiation was considered "Exposure level". Vitamin D levels were categorized into quartiles (≤ 10, 11-20, 21-30, >30 ng/ml). SIM was identified

SUBMITTER: Palamaner Subash Shantha G 

PROVIDER: S-EPMC3929495 | biostudies-literature | 2014

REPOSITORIES: biostudies-literature